Is a combination of assays really needed for non-animal prediction of skin sensitization potential? Performance of the GARD™ (Genomic Allergen Rapid Detection) assay in comparison with OECD guideline assays alone and in combination
Regulatory Toxicology and Pharmacology, Volume 98, October 2018, Pages 155-160, https://doi.org/10.1016/j.yrtph.2018.07.014. David W.Roberts Highlights Prediction of skin sensitization potential does not need multiple assays representing Key Events of the AOP. This has been argued on theoretical grounds and is now tested against published data. A single assay, GARD™, can outperform combinations of OECD test guideline […]
