Skin sensitizing hazard prediction with high accuracy and broad applicability

GARDskin is a robust in vitro test to identify potential chemical skin sensitizers with broad applicability and over 90% prediction accuracy.

The test provides a binary prediction, classifying the test samples into either a skin sensitizers or non-sensitizer.


GARDskin is included in the OECD Test Guideline Program (TGP 4.106). The ESAC has issued a positive opinion on the test method and recommends it be adopted as an OECD Test Guideline for skin sensitization:

Depending on the regulatory context, positive results obtained with GARDskin may be used stand-alone to identify skin sensitizers. Furthermore, the ESAC considers that GARDskin is a functional and valid test method ready for use in industrial screening applications.

GARDskin is accepted by the ECHA as weight-of-evidence in REACH dossiers for skin sensitization assessment (Key event 3).

Do you have “difficult-to-test” samples?

We have successfully tested over 500 samples in GARDskin at SenzaGen’s lab. Many of them are considered “difficult-to-test” with traditional in vitro methods. For example:

  • Complex mixtures
  • Pre- and pro- haptens
  • Surfactants

To learn more about how GARDskin can help you with skin sensitization assessment, visit our “difficult-to-test” page or contact our specialists.

200 genes

The number of biomarkers used in GARDskin.