Skin sensitizing hazard prediction with high accuracy and broad applicability
GARDskin is a robust in vitro test to identify potential chemical skin sensitizers with broad applicability and over 90% prediction accuracy.
The test provides a binary prediction, classifying the test samples into either a skin sensitizers or non-sensitizer.
GARDskin is included in the OECD Test Guideline Program (TGP 4.106). The ESAC has issued a positive opinion on the test method and recommends it be adopted as an OECD Test Guideline for skin sensitization:
Depending on the regulatory context, positive results obtained with GARDskin may be used stand-alone to identify skin sensitizers. Furthermore, the ESAC considers that GARDskin is a functional and valid test method ready for use in industrial screening applications.
GARDskin is accepted by the ECHA as weight-of-evidence in REACH dossiers for skin sensitization assessment (Key event 3).
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Do you have “difficult-to-test” samples?
We have successfully tested over 500 samples in GARDskin at SenzaGen’s lab. Many of them are considered “difficult-to-test” with traditional in vitro methods. For example:
- Complex mixtures
- Pre- and pro- haptens
To learn more about how GARDskin can help you with skin sensitization assessment, visit our “difficult-to-test” page or contact our specialists.
The number of biomarkers used in GARDskin.