GARD^®air.

In vitro hazard identification of
respiratory sensitizers

Powered by genomics and machine learning, GARDair offers a non-animal solution for respiratory hazard assessment, supporting decision making in product development and safety assessment.

The assay provides a binary classification of test items as respiratory sensitizers or non-sensitizers. With 95% specificity, GARDair yields very few false positives, allowing efficient removal of sensitizing candidates and reducing unnecessary follow-up work.

GARDair supports respiratory safety assessments across chemicals, biotech, and pharmaceutical industries and is also suitable for evaluating hazards in occupational health and workplace safety contexts.

Complementary potency assessment

For identified respiratory sensitizers, a dose-response extension of the standard protocol can be applied to generate quantitative potency information for downstream risk assessment and prioritization.

Integrated testing strategies

GARDair can also be combined with other in vitro and in silico methods as part of weight-of-evidence or defined approach frameworks commonly applied in regulatory toxicology.