Bringing high performance and extended applicability to Defined Approaches for Skin Sensitization (DASS)
Join us for a special re-run of our popular webcast to learn more about the inclusion of GARD®skin in OECD TG 497 — what it means and how it can support your regulatory testing strategy.
Defined Approaches for Skin Sensitization (DASS) is a key regulatory guideline for combining validated in vitro methods to support hazard and potency assessment. The GARDskin assay is now part of two Defined Approaches (DAs):
- The “2 out of 3” DA for hazard identification.
- The Integrated Testing Strategy (ITS) for hazard identification and potency sub-categorization (1A, 1B, NC).
With demonstrated high performance and broad applicability to hydrophobic substances (Log P > 3.5) and other challenging chemical entities, GARDskin improves the performance and extends the overall applicability of DASS, helping to fill data gaps in regulatory skin sensitization testing.
Agenda
- Introduction to skin sensitization testing and GARD technology.
- GARDskin (OECD TG 442E) and its inclusion in OECD TG 497.
- Case studies: Improving performance and extending the applicability of DASS for challenging samples.
- Live Q&A.
Speakers
Andy Forreryd, PhD
Scientific Liaison Manager @ SenzaGen
- Co-developer of the GARD®skin assay (OECD TG 442E).
- Member of the ISO/TC 194/WG 8 on irritation and sensitization.
- Member of OECD expert group on respiratory sensitization.
Henrik Johansson, PhD
Chief Scientist @ SenzaGen
- Co-developer of the GARD®skin assay (OECD TG 442E).
- Member of the ISO/TC 194/WG 8 for Irritation and Sensitization.
- Member of the OECD Expert Group on Defined Approaches on Skin Sensitization.
The webinar will last around 40 minutes, followed by a live Q&A. If you cannot attend the live event, register anyway to receive the on-demand recording.
