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Poster presented at ACT 2020: Applicability of GARD™skin for Accurate Assessment of Challenging Substances in the Context of Skin Sensitization Testing

20 November, 2020 in , , , /by

J. Schmidt, A. Forreryd, H. Johansson, J. Li, A. Johansson SenzaGen, Inc., Raleigh, NC, USA, SenzaGen AB, Lund, Sweden   Link to the poster   Conclusion GARDskin demonstrated an overall high applicability for the evaluated challenging substances with 80% predictive accuracy compared to existing human data. GARDskin demonstrated excellent applicability for pre/pro-haptens and low water […]

Poster presented at ACT 2020: Dose-Response Analysis in GARD™ for Assessment of Skin Sensitizer Potency

20 November, 2020 in , , /by

J. Schmidt, A. Forreryd, R. Gradin2, H. Johansson. SenzaGen Inc., Raleigh, NC., SenzaGen AB, Lund, Sweden.   Link to the poster   Conclusion As an adaptation from the GARDskin assay, GARDskin Dose-Response is suitable for quantitative skin sensitizing potency assessment of chemicals. The experimental readout, referred to as cDV0, corresponds to the lowest dose required […]