Entries by Julia Li

Quantitative assessment of sensitizing potency using a dose-response adaptation of GARDskin

Nature Scientific Reports 11, 18904 (2021), https://doi.org/10.1038/s41598-021-98247-7 Robin Gradin, Andy Forreryd, Ulrika Mattson, Anders Jerre, Henrik Johansson Abstract Hundreds of chemicals have been identified as skin sensitizers. These are chemicals that possess the ability to induce hypersensitivity reactions in humans, giving rise to a condition termed allergic contact dermatitis. The capacity to limit hazardous exposure to […]

Reliable and Truly Animal-Free Skin Sensitization Testing – Adaption of the In vitro GARD™skin to Animal-Free Conditions

Poster presented at the 2021 World Congress on Alternatives and Animal Use in the Life Sciences Andy Forreryd, Anders Jerre, Fiona Jacobs, Carol Treasure, Henrik Johansson | SenzaGen AB, 22381 Lund, Sweden; XCellR8 Ltd, Techspace One, Sci-Tech Daresbury, Cheshire WA4 4AB, UK   Download a copy   Conclusion Senzacells adapted well to routine culture in […]

Hazard Assessment of Photoallergens Using GARD™skin

Poster presented at the 2021 World Congress on Alternatives and Animal Use in the Life Sciences Andy Forreryd, Angelica Johansson, Gretchen Ritacco, Anne Marie Api, Henrik Johansson | SenzaGen AB, 22381 Lund, Sweden; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.   Download a copy   Conclusion The GARDskin […]

The GARD™potency assay for potency-associated subclassification of chemical skin sensitizers – Rationale, method development and ring trial results of predictive performance and reproducibility

Poster presented at the 2021 World Congress on Alternatives and Animal Use in the Life Sciences Robin Gradin, Angelica Johansson, Andy Forreryd, Amber Edwards, Veronika Hoepflinge, Florence Burleson, Helge Gehrke, Erwin Roggen, Henrik Johansson| SenzaGen AB, 22381 Lund, Sweden; Burleson Research Technologies, Morrisville, NC 27560, USA; Eurofins BioPharma Product Testing Munich Gmbh, 82152 Planegg, Germany; […]

Quantitative Sensitizing Potency Assessment Using GARD™skin Dose-Response

Poster presented at the 2021 World Congress on Alternatives and Animal Use in the Life Sciences Henrik Johansson, Robin Gradin, Andy Forreryd, Joshua Schmidt SenzaGen AB, Lund, Sweden. SenzaGen Inc., Raleigh, NC. Download a copy   Conclusion As an adaptation from the GARDskin assay, GARDskin Dose-Response is suitable for quantitative skin sensitizing potency assessment of […]

New distribution agreement with Enthalpy Analytical, USA

We are happy to team up with Enthalpy Analytical by welcoming them as distributor of our innovative GARD technology. Based in the USA, Enthalpy is an established CRO in the field of in vitro toxicology, and we jointly strive to provide our clients with best-in-class testing support, innovative science, and high-quality data. Joint marketing activities […]

Applicability domain of the GARD™skin Medical Device test for in vitro skin sensitization testing of medical devices

Poster presented at SOT 2021 Joshua Schmidt, Ron Brown and Rose-Marie Jenvert SenzaGen Inc., Raleigh, NC, USA, Risk Science Consortium LLC, Arnold, MD, USA, SenzaGen AB, Lund, Sweden. Download a copy Conclusion The chemical space of compounds tested in GARD closely approximates the chemical space of compounds known to be released from medical device materials. […]

Quantitative Sensitizing Potency Assessment Using GARD™skin Dose-Response

Poster presented at SOT 2021 Henrik Johansson, Robin Gradin, Andy Forreryd, Joshua Schmidt SenzaGen AB, Lund, Sweden. SenzaGen Inc., Raleigh, NC. Download a copy   Conclusion As an adaptation from the GARDskin assay, GARDskin Dose-Response is suitable for quantitative skin sensitizing potency assessment of chemicals. The experimental readout, referred to as cDV0, corresponds to the […]

SOT 2021 Recap: Spotlight on Dose-Response and the MDCPSS Best Overall Abstract Award Winner 🏅

SenzaGen had a busy program at SOT 2021. To highlight our expanding capabilities in in vitro skin toxicology, we took part in several activities and presented our novel assays for quantitative skin sensitizing potency assessment and medical device testing.   Exhibitor Hosted Session: Dose-response for predicting skin sensitization potency Listen to SenzaGen’s Chief Scientist Dr Henrik Johansson presenting […]