In Vitro Cytotoxicity.
ISO 10993-5: MTT & MEM Elution Test
The MTT cytotoxicity test provides a quantitative measurement of cell viability, and the MEM Elution Test provides a qualitative measurement of cell viability.
Both tests are performed on mouse fibroblast exposed to test item extracts prepared according to ISO 10993-12.
The tests are regulatory accepted and are applied according to ISO 10993-5.
A highly accurate and ethical alternative to animal testing
Our GLP-certified laboratories provide in vitro biocompatibility testing addressing the three endpoints that all medical devices are subjected to assess:
- Cytotoxicity: ISO 10993-5
- Irritation on skin and other epithelia: ISO 10993-23 using 3D reconstructed human tissues
- Skin sensitization: ISO 10993-10 using GARD®skin Medical Device
with over 90% accuracy and demonstrated applicability for use with the extraction vehicles saline and oil
