Science behind.

Chemical hypersensitivity (also called chemical allergy) is a disease state induced by the immune system in response to chemical sensitizers and is initiated by a process called sensitization. Chemicals that are frequently reported to induce sensitization include metal ions, fragrances and cosmetic additives and dyes. Sensitizers are typically small molecule chemicals which are able to penetrate the skin, where they interact with and activate Dendritic cells and initiate an immune response.

Sensitization occours when T cells learn to recognize a specific sensitizer. Following subsequent exposure, the primed T cells – which have now established an immunological memory – react rapidly to induce a state of inflammation. This in turn leads to the disease-associated symptoms of allergic contact dermatitis, such as itching, blistering and tissue damage.