Irritation.
ISO 10993-23: Skin Irritation
We help you access the skin irritation potential of Medical Devices, Medical Device components or extracts using 3D Reconstructed Human Epidermis (RhE) models.
The test method classifies your Medical Devices or materials as skin irritants or non-irritants based on the cell viability outcomes after 24h exposure and 50% cell viability threshold.
Polar and non-polar extracts of the test item are prepared according to ISO 10993-12.
Special irritation tests
In accordance with ISO 10993-23, we offer irritation testing on a range of tissues other than skin, including:
- Corneal
- Vaginal
- Oral
- Esophageal
- Nasal
- Ocular
- Colorectal
- Intestinal
An ethical and accurate alternative to animal testing
Our GLP-compliant laboratories provide in vitro biocompatibility testing addressing the three endpoints that all medical devices are subjected to assess:
