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SenzaGen approved for trading on Nasdaq First North

THIS PRESS RELEASE WAS ORIGINALLY RELEASED IN SWEDISH FOR THE SWEDISH MARKET AND HAS LATER BEEN TRANLSATED TO ENGLISH FOR GENERAL AWARENESS ON THE GLOBAL MARKET

SenzaGen AB (“SenzaGen” or “the Company”) has today been approved by Nasdaq Stockholm AB as an issuer of shares on Nasdaq First North in Stockholm. The first trading day for the Company’s shares is 21st September 2017.

At the request of Nasdaq Stockholm AB, the Company has provided certain additional information relating to its listing on Nasdaq First North, and this information has been collated in the document “Additional information in relation to listing on Nasdaq First North” which is available on the Company’s website www.senzagen.com/investors/prospekt-listning-nasdaq-first-north/.

The share offer for listing on Nasdaq First North
The application period for SenzaGen’s offer for the Company’s listing on Nasdaq First North ended on September 12th 2017. The offer was addressed to both institutional and professional investors as well as to the general public in Sweden. Through the share issue, the Company has acquired more than 1,000 new shareholders.

Certified Adviser and Issuing agent
Vator Securities are the Company’s financial adviser and Baker McKenzie is the Company’s legal adviser. The issuing agent for the transaction is Nordnet Bank.

Further information
For further information, please refer to the Prospectus, which has been approved by and registered with the Swedish Financial Supervisory Authority with regard to the share issue, prior to the planned listing on Nasdaq First North. NOT RELEVANT FO MARKET OUTSIDE SWEDEN

For further information, please visit the Company’s website, www.senzagen.com or contact: Anki Malmborg Hager, CEO of SenzaGen AB, email: anki.malmborg.hager@senzagen.com, telephone: +46 76 828 48 22.

About GARD
GARD is a group of tests for assessing chemical skin sensitizers. The tests make use of genetic biomarkers for more than 200 genes which cover the entire immune reaction and are relevant to predicting the risk of hypersensitivity. The tests have up to 90% reliability.

This compares with the current predominant test method, experiments on mice, which has an accuracy of 70-75%. SenzaGen’s tests are also capable of measuring the potency of a substance’s allergenic properties. Consequently, GARD tests provide a much more comprehensive basis for determining whether a substance should be classified as an allergen than current testing methods.

About SenzaGen
SenzaGen makes it possible to replace animal experiments with in vitro genetic testing to determine the allergenicity of the chemicals we come into contact with in our daily lives, such as for example in cosmetics, pharmaceuticals, food products and dyes. The company’s patented tests are the most reliable on the market and provide more information than traditional evaluation methods. We ourselves sell the tests in Sweden and the USA, and we sell through partners in several other countries. Over the next few years the company will expand geographically, make alliances with more distribution partners and launch further unique tests. SenzaGen has its headquarters in Lund in Sweden and a subsidiary in San Francisco, USA. For more information visit www.senzagen.com 

Important information
This announcement is not and does not form a part of any offer for sale of securities.

Copies of this announcement are not being made and may not be distributed or sent into the United States, Australia, Canada, Japan, New Zealand, South Africa, Hong Kong, Singapore or any other jurisdiction in which such distribution would be unlawful or would require registration or other measures. The securities referred to in this announcement have not been and will not be registered under the U.S. Securities Act of 1933, as amended (the “Securities Act”), and accordingly may not be offered or sold in the United States absent registration or an exemption from the registration requirements of the Securities Act and in accordance with applicable U.S. state securities laws. The Company does not intend to register any offering in the United States or to conduct a public offering of securities in the United States.

An offering of the securities referred to in this announcement is made by means of the prospectus referred to herein. This announcement is not a prospectus for the purposes of Directive 2003/71/EC (together with any applicable implementing measures in any Member State, the “Prospectus Directive”). Investors should not invest in any securities referred to in this announcement except on the basis of information contained in the aforementioned prospectus.

Matters discussed in this announcement may constitute forward-looking statements. Forward-looking statements are statements that are not historical facts and may be identified by words such as “believe,” “expect,” “anticipate,” “intends,” “estimate,” “will,” “may,” “continue,” “should” and similar expressions. The forward-looking statements in this release are based upon various assumptions, many of which are based, in turn, upon further assumptions. Although the Company believes that these assumptions were reasonable when made, these assumptions are inherently subject to significant known and unknown risks, uncertainties, contingencies and other important factors which are difficult or impossible to predict and are beyond its control. Such risks, uncertainties, contingencies and other important factors could cause actual events to differ materially from the expectations expressed or implied in this release by such forward-looking statements. The information, opinions and forward-looking statements contained in this announcement speak only as at its date, and are subject to change without notice.

Press release in pdf

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SenzaGen’s share offer heavily oversubscribed prior to listing on Nasdaq First North

THIS PRESS RELEASE WAS ORIGINALLY RELEASED IN SWEDISH FOR THE SWEDISH MARKET AND HAS LATER BEEN TRANLSATED TO ENGLISH FOR GENERAL AWARENESS ON THE GLOBAL MARKET

The offer of shares in SenzaGen AB (“SenzaGen” or “the Company”) prior to the Company’s listing on Nasdaq First North was heavily oversubscribed. The Company expects to raise SEK 90.1 million through this new share offer, before issue costs. Estimated first day of trading in the Company’s shares on Nasdaq First North is 21th September 2017, provided that Nasdaq Stockholm AB approves the Company’s application.

The application period for SenzaGen’s offer ended on September 12th 2017. The offer was addressed to both institutional and professional investors, as well as the general public in Sweden. When the offer has been registered with the Swedish Companies Registration Office (Bolagsverket), the number of shares will increase by 4,645,000 to a total of 15,461,000 shares. Through the share issue, the Company has acquired more than 1,000 new shareholders.

Subscription undertakings
Prior to the subscription period, most existing as well as new institutional and qualified investors had undertaken to subscribe in advance for shares to a total of approximately SEK 75 million, corresponding to 83 percent of the offer. Among those who undertook to subscribe in advance are Ålandsbanken Funds Ltd, Leif GW Persson, Jörgen Book (formerly with global market responsibility for strategy and pricing of respiratory products at AstraZeneca) and Per Lindberg (former global technology analyst and now an investor).

Certified Adviser and Issuing agent
Vator Securities are the Company’s financial adviser and Baker McKenzie is the Company’s legal adviser. The issuing agent for the transaction is Nordnet Bank.

Further information
For further information, please refer to the Prospectus (available in Swedish only), which has been approved by and registered with the Swedish Financial Supervisory Authority with regard to the share issue, prior to the planned listing on Nasdaq First North.

For further information, please visit the Company’s website, www.senzagen.com or contact: Anki Malmborg Hager, CEO of SenzaGen AB, email: anki.malmborg.hager@senzagen.com, telephone: +46 76 828 48 22.

About GARD
GARD is a group of tests for assessing chemical skin sensitizers. The tests make use of genetic biomarkers for more than 200 genes which cover the entire immune reaction and are relevant to predicting the risk of hypersensitivity. The tests have up to 90% reliability.

This compares with the current predominant test method, experiments on mice, which has an accuracy of 70-75%. SenzaGen’s tests are also capable of measuring the potency of a substance’s allergenic properties. Consequently, GARD tests provide a much more comprehensive basis for determining whether a substance should be classified as an allergen than current testing methods.

About SenzaGen
SenzaGen makes it possible to replace animal experiments with in vitro genetic testing to determine the allergenicity of the chemicals we come into contact with in our daily lives, such as for example in cosmetics, pharmaceuticals, food products and dyes. The company’s patented tests are the most reliable on the market and provide more information than traditional evaluation methods. We ourselves sell the tests in Sweden and the USA, and we sell through partners in several other countries. Over the next few years the company will expand geographically, make alliances with more distribution partners and launch further unique tests. SenzaGen has its headquarters in Lund in Sweden and a subsidiary in San Francisco, USA. For more information visit www.senzagen.com 

Important information
This announcement is not and does not form a part of any offer for sale of securities.

Copies of this announcement are not being made and may not be distributed or sent into the United States, Australia, Canada, Japan, New Zealand, South Africa, Hong Kong, Singapore or any other jurisdiction in which such distribution would be unlawful or would require registration or other measures. The securities referred to in this announcement have not been and will not be registered under the U.S. Securities Act of 1933, as amended (the “Securities Act”), and accordingly may not be offered or sold in the United States absent registration or an exemption from the registration requirements of the Securities Act and in accordance with applicable U.S. state securities laws. The Company does not intend to register any offering in the United States or to conduct a public offering of securities in the United States.

An offering of the securities referred to in this announcement is made by means of the prospectus referred to herein. This announcement is not a prospectus for the purposes of Directive 2003/71/EC (together with any applicable implementing measures in any Member State, the “Prospectus Directive”). Investors should not invest in any securities referred to in this announcement except on the basis of information contained in the aforementioned prospectus.

Matters discussed in this announcement may constitute forward-looking statements. Forward-looking statements are statements that are not historical facts and may be identified by words such as “believe,” “expect,” “anticipate,” “intends,” “estimate,” “will,” “may,” “continue,” “should” and similar expressions. The forward-looking statements in this release are based upon various assumptions, many of which are based, in turn, upon further assumptions. Although the Company believes that these assumptions were reasonable when made, these assumptions are inherently subject to significant known and unknown risks, uncertainties, contingencies and other important factors which are difficult or impossible to predict and are beyond its control. Such risks, uncertainties, contingencies and other important factors could cause actual events to differ materially from the expectations expressed or implied in this release by such forward-looking statements. The information, opinions and forward-looking statements contained in this announcement speak only as at its date, and are subject to change without notice.

Press release in pdf

SenzaGen to present at EUROTOX Congress in Slovakia

SenzaGen announces today that the company will be presenting two scientific abstracts and hold a presentation titled “21st century testing: Can one test be stand alone?” at the upcoming EUROTOX Congress in Bratislava, Slovakia.

The 53rd European Congress of the European Societies of Toxicology, EUROTOX, is to be held in Bratislava, Slovakia on September 10-13, 2017. The congress will include a multitude of symposia and workshops as well as a large exhibition area and is an important meeting point for research community and industry.

On 12 September, SenzaGen’s new Chief Scientific Officer Henrik Appelgren will give an Exhibitor Hosted presentation at the congress with the full title “21st century testing for skin sensitisation: Can one test be stand alone? Regulatory challenges and GARD applications update” Furthermore, SenzaGen is also exhibiting at the congress (Booth 25) and is presenting two scientific posters on the transferability of the GARDskin assay to two independent laboratories and the GARD platform for potency assessment of skin sensitizing chemicals.

For additional information regarding Henrik Appelgren’s presentation, visit:
www.eurotox2017.com/programme/exhibitors-meetings/senzagen/
or SenzaGen web site www.senzagen.com/event-calendar/

For more information:
Anki Malmborg Hager, CEO, SenzaGen AB
Email: anki.malmborg.hager@senzagen.com
Telephone: +46 768 284822

About GARD
GARD™ is a group of tests for assessing chemical skin sensitizers. The tests make use of genetic biomarkers for more than 200 genes which cover the entire immune reaction and are relevant to predicting the risk of hypersensitivity. The tests have 90% reliability. This compares with the current predominant test method, experiments on mice, which has a reliability rating of 72%. SenzaGen’s tests are also capable of measuring the potency of a substance’s allergenic properties. Consequently GARD tests provide a much more comprehensive basis for determining whether a substance should be classified as an allergen than current testing methods.

About SenzaGen
SenzaGen makes it possible to replace animal experiments with in vitro genetic testing to determine the allergenicity of the chemicals we come into contact with in our daily lives, such as for example in cosmetics, pharmaceuticals, food products and dyes. The company’s patented tests are the most reliable on the market and provide more information than traditional evaluation methods. We ourselves sell the tests in Sweden and the USA, and we sell through partners in several other countries. Over the next few years the company will expand geographically, make alliances with more distribution partners and launch further unique tests. SenzaGen has its headquarters in Lund in Sweden and a subsidiary in San Francisco, USA. For more information visit www.senzagen.com.

Press release in pdf

 

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SenzaGen publishes Prospectus prior to listing on Nasdaq First North

THIS PRESS RELEASE WAS ORIGINALLY RELEASED IN SWEDISH FOR THE SWEDISH MARKET AND HAS LATER BEEN TRANLSATED TO ENGLISH FOR GENERAL AWARENESS ON THE GLOBAL MARKET.

NOT FOR PUBLICATION, DISTRIBUTION OR RELEASE DIRECTLY OR INDIRECTLY, IN WHOLE OR IN PART, IN OR INTO THE UNITED STATES, AUSTRALIA, CANADA, JAPAN OR REPUBLIC OF SOUTH AFRICA OR IN ANY OTHER JURISDICTION IN WHICH OFFERS OR SALES WOULD BE PROHIBITED BY APPLICABLE LAW.

SenzaGen AB (“SenzaGen” or “the Company”) announces a public offering of the Company’s shares and applies for listing of these shares on Nasdaq First North in Stockholm (“the Offer”). The Company has therefore prepared a prospectus (“the Prospectus”) which has today been approved by and registered with Finansinspektionen, the Swedish Financial Supervisory Authority. The Prospectus is now available on the Company’s website, www.senzagen.com/investors, and elsewhere.

SenzaGen has decided to offer shares in the Company to the general public in Sweden and Denmark (with certain restrictions) as well as to institutional investors in Sweden and abroad, and is therefore applying for listing on Nasdaq First North in Stockholm. The purpose of the Offer is to finance the expansion of the Company’s sales organization and its existing product portfolio with new tests based on the existing GARD platform.

The Offer and the subsequent listing on Nasdaq First North will give the Company access to capital markets, create liquidity in the Company’s shares, and also bring new shareholders to SenzaGen, thereby strengthening the Company’s development. SenzaGen’s listing is also expected to have a positive effect on the Company’s relationships with partners and potential customers.

The offer in brief

  • The Offer consists of up to 4,645,000 shares.
  • The subscription price has been set at 19.40 SEK per share.
  • The Offer amounts to a total of approximately SEK 90 million.
  • The portion of the Offer relating to the general public in Denmark is limited to shares totalling less than 1 million euros or equivalent amount in SEK.
  • The total Offer corresponds to a valuation of SenzaGen of approximately SEK 210 million (pre-money).
  • The application period for the public will last from 4thSeptember to 12th September 2017.
  • The settlement date is September 19th
  • Estimated first day of trading, provided that Nasdaq Stockholm AB approves the Company’s application, is September 21st

The application form will be available on SenzaGen’s website, www.senzagen.com/investors, Vator Securities website, www.vatorsecurities.se and Nordnet’s website, www.nordnet.se/emissioner, throughout the application period.

Subscription undertakings
The majority of existing as well as new institutional and qualified investors have already undertaken to subscribe for shares to a total of approximately SEK 75 million, equivalent to 83 percent of the Offer. Among these are Ålandsbanken Funds Ltd, Leif GW Persson, Jörgen Book, formerly with global market responsibility for strategy and pricing of respiratory products at AstraZeneca, and Per Lindberg, former global technology analyst and now an investor.

The Prospectus
For full details of the Offer, please refer to the Prospectus (available in Swedish only). The Prospectus has today been approved by and registered with the Swedish Financial Supervisory Authority (Finansinspektionen) and is available on SenzaGen’s website, www.senzagen.com/investors, Vator Securities website, www.vatorsec.se and will be available on the Finansinspektionen website, www.fi.se, within a few days.

Certified Adviser and Issuing agent
Vator Securities are the Company’s financial adviser and Baker McKenzie is the Company’s legal adviser. The issuing agent for the transaction is Nordnet Bank.


Further information

For further information, please refer to the Prospectus, which has been approved by and registered with the Swedish Financial Supervisory Authority with regard to the share issue, prior to the planned listing on Nasdaq First North.

For further information, please visit the Company’s website, www.senzagen.com or contact: Anki Malmborg Hager, CEO of SenzaGen AB, email: anki.malmborg.hager@senzagen.com, telephone: +46 76 828 48 22.

About GARD
GARD is a group of tests for assessing chemical skin sensitizers. The tests make use of genetic biomarkers for more than 200 genes which cover the entire immune reaction and are relevant to predicting the risk of hypersensitivity. The tests have up to 90% reliability.

This compares with the current predominant test method, experiments on mice, which has an accuracy of 70-75%. SenzaGen’s tests are also capable of measuring the potency of a substance’s allergenic properties. Consequently, GARD tests provide a much more comprehensive basis for determining whether a substance should be classified as an allergen than current testing methods.

About SenzaGen
SenzaGen makes it possible to replace animal experiments with in vitro genetic testing to determine the allergenicity of the chemicals we come into contact with in our daily lives, such as for example in cosmetics, pharmaceuticals, food products and dyes. The company’s patented tests are the most reliable on the market and provide more information than traditional evaluation methods. We ourselves sell the tests in Sweden and the USA, and we sell through partners in several other countries. Over the next few years the company will expand geographically, make alliances with more distribution partners and launch further unique tests. SenzaGen has its headquarters in Lund in Sweden and a subsidiary in San Francisco, USA. For more information visit www.senzagen.com 

Important information

This announcement is not and does not form a part of any offer for sale of securities.

Copies of this announcement are not being made and may not be distributed or sent into the United States, Australia, Canada, Japan, New Zealand, South Africa, Hong Kong, Singapore or any other jurisdiction in which such distribution would be unlawful or would require registration or other measures. The securities referred to in this announcement have not been and will not be registered under the U.S. Securities Act of 1933, as amended (the “Securities Act”), and accordingly may not be offered or sold in the United States absent registration or an exemption from the registration requirements of the Securities Act and in accordance with applicable U.S. state securities laws. The Company does not intend to register any offering in the United States or to conduct a public offering of securities in the United States.

An offering of the securities referred to in this announcement is made by means of the prospectus referred to herein. This announcement is not a prospectus for the purposes of Directive 2003/71/EC (together with any applicable implementing measures in any Member State, the “Prospectus Directive”). Investors should not invest in any securities referred to in this announcement except on the basis of information contained in the aforementioned prospectus.

Matters discussed in this announcement may constitute forward-looking statements. Forward-looking statements are statements that are not historical facts and may be identified by words such as “believe,” “expect,” “anticipate,” “intends,” “estimate,” “will,” “may,” “continue,” “should” and similar expressions. The forward-looking statements in this release are based upon various assumptions, many of which are based, in turn, upon further assumptions. Although the Company believes that these assumptions were reasonable when made, these assumptions are inherently subject to significant known and unknown risks, uncertainties, contingencies and other important factors which are difficult or impossible to predict and are beyond its control. Such risks, uncertainties, contingencies and other important factors could cause actual events to differ materially from the expectations expressed or implied in this release by such forward-looking statements. The information, opinions and forward-looking statements contained in this announcement speak only as at its date, and are subject to change without notice.

Press release in pdf

SenzaGen’s chairman Carl Borrebaeck has received the Biotech Builders Award 2017

SenzaGen’s chairman, Professor Carl Borrebaeck, has received the prestigious BiotechBuilders Award for his ground-breaking medical research and prominent role as entrepreneur in Life Science, including being the co-founder of SenzaGen, Immunovia, Alligator Bioscience and BioInvent. The award was announced at the annual BiotechBuilder’s meeting in Stockholm on 28 August. Through his involvement in SenzaGen, Carl Borrebaeck has contributed to the development of GARD™ – a gene-based test that evaluates the allergenic properties of chemical substances, thus eliminating the need for animal testing.

Carl Borrebaeck was given the award on the grounds of being a successful entrepreneur who contributed to the start of several new life science companies, including, Alligator Bioscience, Immunovia, BioInvent and SenzaGen, of which the first three have been introduced on the Swedish stock market. His efforts to build scientific networks, including Medicon Village, NOME (Nordic Mentor Network for Entrepreneurship) and Cancer Crosslink Conference, also contribute to his election as an outstanding “biotech builder” and good representative of Swedish life science industry.

Carl Borrebaeck’s latest start-up company SenzaGen, has its base at Medicon Village in Lund. The company develops and sells allergy tests, mainly to the cosmetics and chemical industry. SenzaGen’s test, the GARD™ (Genomic Allergen Rapid Detection) is an alternative method for allergy testing that eliminates the need for animal testing. The method has been developed for over 10 years by a research group at Lund University, led by Carl Borrebaeck, Professor and at the time Head of Institution, and Malin Lindstedt, Professor and Senior Lecturer, both at the Institution of Immunotechnology. GARD utilizes the human genome to classify chemicals, and evaluate their ability to induce allergic reactions in human cells. Today, SenzaGen owns the patents and drives the development as well as the global marketing and sales of GARD. SenzaGen is planning a listing on Nasdaq First North in September 2017.

For more information:
Anki Malmborg Hager,
CEO, SenzaGen AB
Email:  anki.malmborg.hager@senzagen.com
Phone:  +46 768 284822

About GARD
GARD™ is a group of tests for assessing chemical skin sensitizers. The tests make use of genetic biomarkers for more than 200 genes which cover the entire immune reaction and are relevant to predicting the risk of hypersensitivity. The tests have 90% reliability. This compares with the current predominant test method, experiments on mice, which has a reliability rating of 72%. SenzaGen’s tests are also capable of measuring the potency of a substance’s allergenic properties. Consequently GARD tests provide a much more comprehensive basis for determining whether a substance should be classified as an allergen than current testing methods.

About SenzaGen
SenzaGen makes it possible to replace animal experiments with in vitro genetic testing to determine the allergenicity of the chemicals we come into contact with in our daily lives, such as for example in cosmetics, pharmaceuticals, food products and dyes. The company’s patented tests are the most reliable on the market and provide more information than traditional evaluation methods. We ourselves sell the tests in Sweden and the USA, and we sell through partners in several other countries. Over the next few years the company will expand geographically, make alliances with more distribution partners and launch further unique tests. SenzaGen has its headquarters in Lund in Sweden and a subsidiary in San Francisco, USA. For more information visit www.senzagen.com

About Biotech Builders
BiotechBuilders was first initiated in Denmark, 2002, by Dr Jørgen Thorball an early morning at Copenhagen Airport.  The news about the dying Biotech industry called for action to energize the entrepreneurs and bring new life to the industry. Dr Torberg invited the leading life science companies to initiate the first BiotechBuilders event. In this playful and inspiring environment, company founders, visionaries, venture capitalist and CEOs had the opportunity to network and exchange ideas. In 2009 the event was brought to Sweden and have since been held annually in Stockholm, and it has been a great success and much appreciated among the participating people.

Press release in pdf

SenzaGen secures patent protection for its GARDskin™ test in Europe

SenzaGen announces today that the European Patent Office (EPO) has granted a patent for GARDskin, the company’s recently launched test that determines whether chemical substances may induce skin allergies. GARD™ tests are significantly more reliable than traditional evaluation methods, and provide more comprehensive information on the allergy-inducing properties of the chemicals studied. Hence, GARDconfers increased protection level for humans. The test is carried out in vitro, thus eliminating the need for animal testing.

The recently granted European patent covers the analytical methods and genetic signatures that form the foundation of SenzaGen´s proprietary GARDskin™ technology. The patent is valid until October 2031.

“This affirmation from the European Patent Office of the merits of our technology is an important milestone in SenzaGen’s strategic plan to establish our unique GARDskin™ test as a new global standard for the industry. Robust patent protection in Europe for GARDskin™ further strengthens our company’s commercial potential and makes us even more attractive to international distribution partners,” says SenzaGen’s CEO, Anki Malmborg Hager.

The announcement from the European Patent Office relates to European Patent No. 2,633077 B, entitled: “Analytical methods and arrays for use in the identification of agents inducing sensitization in human skin”. Corresponding patent applications are currently being processed by the patent authorities in Brazil, Canada, China, Hong Kong, India, South Korea and the United States.

For more information please contact:
Anki Malmborg Hager, CEO, SenzaGen AB
Email: anki.malmborg.hager@senzagen.com
Telephone: +46 768 284822

About GARD
GARD is a group of tests for assessing chemical skin sensitizers. The tests make use of genetic biomarkers for more than 200 genes which cover the entire immune reaction and are relevant to predicting the risk of hypersensitivity. The tests have up to 90% reliability. This compares with the current predominant test method, experiments on mice, which has an accuracy of 70-75%. SenzaGen’s tests are also capable of measuring the potency of a substance’s allergenic properties. Consequently, GARD tests provide a much more comprehensive basis for determining whether a substance should be classified as an allergen than current testing methods.

About SenzaGen
SenzaGen makes it possible to replace animal experiments with in vitro genetic testing to determine the allergenicity of the chemicals we come into contact with in our daily lives, such as for example in cosmetics, pharmaceuticals, food products and dyes. The company’s patented tests are the most reliable on the market and provide more information than traditional evaluation methods. We ourselves sell the tests in Sweden and the USA, and we sell through partners in several other countries. Over the next few years the company will expand geographically, make alliances with more distribution partners and launch further unique tests. SenzaGen has its headquarters in Lund in Sweden and a subsidiary in San Francisco, USA. For more information visit www.senzagen.com

Press release in pdf

SenzaGen recruits Chief Commercial Officer and Chief Scientific Officer

SenzaGen announces today that the company has recruited Anna Chérouvrier Hansson as Chief Commercial Officer and Dr. Henrik Appelgren as Chief Scientific Officer. The company’s management is thus strengthened in the run-up to the commercialization of the company’s GARD tests, which are used to assess the allergenic properties of chemical substances.

Anna Chérouvrier Hansson – CCO, Henrik Appelgren – CSO, Marianne Olsson – CFO, Steve Smith – IP

The appointments announced today are the final stage in the work to strengthen SenzaGen’s management for the commercialization of the GARD tests and the company’s planned listing on Nasdaq First North. The management team has been built up gradually over the past year – at the end of 2016 Marianne Olsson started work as Chief Financial Officer, and in early 2017 Dr Steve Smith was recruited to the post of Intellectual Property Counsel.

“We are delighted to have attracted such well-qualified and industrially experienced people to SenzaGen. The company’s management now has an optimal composition for our work to establish GARD tests as the new global standard for evaluating the allergy-inducing properties of chemical substances,” says SenzaGen CEO Anki Malmborg Hager.

Anna Chérouvrier Hansson, Bachelor of Business Administration, and Master of European Business Administration and Business Law, comes most recently from a position as Director of Marketing at the listed drug company Camurus. There she was responsible for the company’s marketing department, the development and management of the medical device marketing and sales organisation and for the establishment of distribution partnerships in Asia, the USA and France. She has previously worked as Head of Business Development Life Science at Invest in Skåne, Partner at Zitha Consulting and in a number of senior positions in European pharmaceutical and chemical companies.

Henrik Appelgren is a biologist with a PhD in genetic toxicology. He has been working at the Swedish Chemicals Agency for 15 years, where he worked as Sweden’s national coordinator in the OECD Test Guideline Programme. Henrik has a deep knowledge in alternative test methods and of regulatory work in the chemical industry – both nationally and internationally. He also has long experience of health risk assessments of chemicals in all European legislation. He is, or has been, a member of several scientific expert councils including FORMAS, the Swedish Research Council, the Swedish Fund for Research Without Animal Experiments, the Scandinavian Society for Cell Toxicology and EUToxRisk.

Anna Chérouvrier Hansson takes up her position on 15th August and Henrik Appelgren on 4th September 2017.

A complete presentation of SenzaGen’s management team will be available on the company’s website when the positions are started, www.senzagen.com.

For more information:
Anki Malmborg Hager, CEO, SenzaGen AB
Email: anki.malmborg.hager@senzagen.com
Telephone: +46 768 284822

About GARD
GARD is a group of tests for assessing chemical skin sensitizers. The tests make use of genetic biomarkers for more than 200 genes which cover the entire immune reaction and are relevant to predicting the risk of hypersensitivity. The tests have up to 90% reliability. This compares with the current predominant test method, experiments on mice, which has an accuracy of 70-75%. SenzaGen’s tests are also capable of measuring the potency of a substance’s allergenic properties. Consequently GARD tests provide a much more comprehensive basis for determining whether a substance should be classified as an allergen than current testing methods.

About SenzaGen
SenzaGen makes it possible to replace animal experiments with in vitro genetic testing to determine the allergenicity of the chemicals we come into contact with in our daily lives, such as for example in cosmetics, pharmaceuticals, food products and dyes. The company’s patented tests are the most reliable on the market and provide more information than traditional evaluation methods. We ourselves sell the tests in Sweden and the USA, and we sell through partners in several other countries. Over the next few years the company will expand geographically, make alliances with more distribution partners and launch further unique tests. SenzaGen has its headquarters in Lund in Sweden and a subsidiary in San Francisco, USA. For more information visit www.senzagen.com

Press release in pdf

SenzaGen signs global distribution agreement with Charles River Laboratories

SenzaGen announces today that the company has signed a global distribution agreement with Charles River Laboratories, a leading early-stage contract research organization, to market GARDskin to their clients globally. GARDskin has the potential to replace traditional methods in regulatory testing, in accordance with European REACH Regulation.

GARDskin is a genome-based test that – with higher accuracy than the current gold standard test method – reveals whether chemical substances are at risk of causing allergies.

“With this new global distribution agreement, we are linking up with yet another very strong partner for the global launch of GARDskin. Charles River is a leading player in many important geographical markets and in several different industries, and we are looking forward to working together in the commercialization of SenzaGen’s high performing, accurate allergy test,” says SenzaGen CEO Anki Malmborg Hager.

Charles River Laboratories International, Inc. is a global company that specializes in a range of preclinical laboratory services for the pharmaceutical and biotechnology industries. Among its customers are many of the world’s leading pharmaceutical and biotechnology companies, academic institutions and government research centres. The company has more than 11,000 employees worldwide and is listed on the NYSE.

For more information
Anki Malmborg Hager, CEO, SenzaGen AB
Email: anki.malmborg.hager@senzagen.com
Telephone: +46 768 284822

About GARD
GARD is a group of tests for assessing chemical skin sensitizers. The tests make use of genetic biomarkers for more than 200 genes which cover the entire immune reaction and are relevant to predicting the risk of hypersensitivity. The tests have up to 90% reliability. This compares with the current predominant test method, experiments on mice, which has an accuracy of 70-75%. SenzaGen’s tests are also capable of measuring the potency of a substance’s allergenic properties. Consequently GARD tests provide a much more comprehensive basis for determining whether a substance should be classified as an allergen than current testing methods.

About SenzaGen
SenzaGen makes it possible to replace animal experiments with in vitro genetic testing to determine the allergenicity of the chemicals we come into contact with in our daily lives, such as for example in cosmetics, pharmaceuticals, food products and dyes. The company’s patented tests are the most reliable on the market and provide more information than traditional evaluation methods. We ourselves sell the tests in Sweden and the USA, and we sell through partners in several other countries. Over the next few years the company will expand geographically, make alliances with more distribution partners and launch further unique tests. SenzaGen has its headquarters in Lund in Sweden and a subsidiary in San Francisco, USA. For more information visit www.senzagen.com 

Press release in pdf

Positive research results for SenzaGen’s GARDpotency test published in leading scientific journal

SenzaGen announces today that a scientific evaluation of GARDpotency shows that the test reveals with high accuracy whether chemical substances are allergenic and how strong the allergic effect of the chemical is. The results have been published in the prestigious scientific journal Altex. GARDpotency is a gene-based test which is carried out in vitro, thus eliminating the need for animal testing.

The recently published scientific evaluation has been conducted by a research group at Lund University led by Malin Lindstedt, professor and senior lecturer at the Department of Immunotechnology. The research group has been able to identify 52 biomarkers which, with very high accuracy, can quantify the allergenic effect of a chemical substance. GARDpotency is thus able to meet the challenges facing chemical manufacturers as the authorities tighten the requirements for allergy testing at the same time as regulating and prohibiting the use of the animal tests which are currently in use.

“The results of this scientific evaluation underline the fact that GARDpotency has the potential to revolutionize the testing of the chemicals we come into contact with in our daily lives. A significant advantage of GARDpotency is that it enables existing animal-based methods in regulatory testing to be replaced in line with the EU’s REACH regulation,” says SenzaGen CEO Anki Malmborg Hager.

The EU’s chemical substances regulation REACH places strict controls on the evaluation, registration and use of chemical substances. Since 2013 cosmetics may not be allergy tested on animals and, under the REACH regulation, animal-free methods must be used if available. One consequence of this is that chemicals classified as allergenic must also be potency-classified without the use of animal testing. SenzaGen has commenced a limited launch of GARDpotency and is now working to adapt the test method to the needs of industry and to achieve OECD validation.

The scientific report is available via this link:
http://www.altex.ch/resources/Zeller__of_170412_v2.pdf

For more information:
Anki Malmborg Hager, CEO SenzaGen
E-mail: amh@senzagen.com
Phone: +46 768 284822

About GARD
GARD is a group of tests for assessing chemical skin sensitizers. The tests make use of genetic biomarkers for more than 200 genes which cover the entire immune reaction and are relevant to predicting the risk of hypersensitivity. The tests have 90% reliability. This compares with the current predominant test method, experiments on mice, which has a reliability rating of 72%. SenzaGen’s tests are also capable of measuring the potency of a substance’s allergenic properties. Consequently GARD tests provide a much more comprehensive basis for determining whether a substance should be classified as an allergen than current testing methods.

About SenzaGen
SenzaGen makes it possible to replace animal experiments with in vitro genetic testing to determine the allergenicity of the chemicals we come into contact with in our daily lives, such as for example in cosmetics, pharmaceuticals, food products and dyes. The company’s patented tests are the most reliable on the market and provide more information than traditional evaluation methods. We ourselves sell the tests in Sweden and the USA, and we sell through partners in several other countries. Over the next few years the company will expand geographically, make alliances with more distribution partners and launch further unique tests. SenzaGen has its headquarters in Lund in Sweden and a subsidiary in San Francisco, USA. For more information visit www.senzagen.com

Press release in pdf

SenzaGen and AstraZeneca initiate technology development collaboration

SenzaGen has signed a collaboration agreement with the global biopharmaceutical  company AstraZeneca. The collaboration focuses on  testing and development of SenzaGen’s sensitization test GARDair, in order to distinguish between allergens and irritants in the respiratory tract. The goal is the validation of in vitro toxicological tests that could be applied to the discovery of new treatments for respiratory diseases without respiratory tract irritancy as a side effect.

The collaboration means that SenzaGen will use its leading technology platform GARD, with the help of AstraZeneca’s well-documented substance libraries, to develop a new genomic signature to distinguish allergens from irritants in the respiratory tract, something which is not possible today with in vitro methods. GARD examines and finds allergens in chemicals and medicines through a unique technology in accordance with the international 3Rs principle, Reduce, Replace and Refine, as an alternative to animal testing.

“During our research and drug discovery activities, it is important to be able to identify and mitigate potential toxicological issues as early as possible, to ensure our novel candidate drugs have the right safety profile for patients. This requires in vitro toxicological methods that are properly validated for their predictivity of clinical toxicity and that are compatible with integration into the drug discovery process. By combining SenzaGen’s technological expertise and our experience with inhaled compounds, we aim to develop a novel method to investigate whether novel drug-like molecules induce similar genomic signatures as known respiratory irritants. That could ultimately be applied to steer away from a potential irritancy hazard and enable the discovery of safer drugs for patients’” says Jorrit Hornberg, Director of Discovery Safety at AstraZeneca Gothenburg.

With this new agreement SenzaGen is initiating yet another important development collaboration with the pharmaceutical industry. SenzaGen’s focus is on introducing its tests into the pharmaceutical industry and on striving to demonstrate that there are safer and more accurate tests than those that use animals.

“This collaboration with AstraZeneca is a milestone for SenzaGen. It shows that leading pharmaceutical companies see the potential of next-generation testing and that this testing has considerable industrial value. Furthermore, the collaboration will provide SenzaGen with valuable knowledge and will help to refine and develop our GARD test for further commercial opportunities,”says
Anki Malmborg Hager, CEO of SenzaGen.

The research project will run for 12 to 18 months and is in collaboration with AstraZeneca Gothenburg, contributing to the EU Horizon 2020 project granted to SenzaGen for the development of in vitro respiratory sensitization test.

For more information:
Anki Malmborg Hager, CEO, SenzaGen AB
E-mail: amh@senzagen.com
Phone: 46 768 284822

About GARD
GARD is a group of tests for assessing chemical skin sensitizers. The tests make use of genetic biomarkers for more than 200 genes which cover the entire immune reaction and are relevant to predicting the risk of hypersensitivity. The tests have 90% reliability. This compares with the current predominant test method, experiments on mice, which has a reliability rating of 72%. SenzaGen’s tests are also capable of measuring the potency of a substance’s allergenic properties. Consequently GARD tests provide a much more comprehensive basis for determining whether a substance should be classified as an allergen than current testing methods.

About SenzaGen
SenzaGen makes it possible to replace animal experiments with in vitro genetic testing to determine the allergenicity of the chemicals we come into contact with in our daily lives, such as for example in cosmetics, pharmaceuticals, food products and dyes. The company’s patented tests are the most reliable on the market and provide more information than traditional evaluation methods. We ourselves sell the tests in Sweden and the USA, and we sell through partners in several other countries. Over the next few years the company will expand geographically, make alliances with more distribution partners and launch further unique tests. SenzaGen has its headquarters in Lund in Sweden and a subsidiary in San Francisco, USA. For more information visit www.senzagen.com.

About AstraZeneca
AstraZeneca is a global, science-led biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines, primarily for the treatment of diseases in three main therapy areas – Oncology, Cardiovascular & Metabolic Diseases and Respiratory. The Company also is selectively active in the areas of autoimmunity, neuroscience and infection. AstraZeneca operates in over 100 countries and its innovative medicines are used by millions of patients worldwide.

Press release in pdf