Entries by Hanna Frykman

Dr. Henrik Johansson, scientist and COO of SenzaGen AB, was awarded the LUSH Young Researcher Award 2014.

“The project for which Dr. Johansson was awarded, the Lush Prize Young Researcher Award, describes the development and use of the novel test method GARD – Genomic Allergen Rapid Detection, an assay for assessment of chemical sensitizers. …GARD utilises an in vitro model of so-called dendritic cells, a central player in the human immune system. […]

SenzaGen recruits Dr. Carl-Henric Nilsson and Ann Gidner to the Board of Directors

-We are entering into a very exciting commercial phase and are happy to be able to engage board members with international experience from our target markets, says Prof. Carl Borrebaeck, chairman of the board of SenzaGen. Carl-Henric Nilsson holds a PhD and M.Sc. in Industrial management, and is Associate Professor at Lund University, School of […]

SenzaGen recruits Dr. Anki Malmborg Hager as CEO

We are very happy to have been able to recruit Dr. Malmborg, who has extensive experience from commercialization of academic results, financial markets and business developments says Prof.Carl Borrebaeck, chairman of the Board of SenzaGen. Anki Malmborg Hager has more than 20 years´ experience in both pharmaceutical and biotech companies that are spin-offs from the […]

Genomic allergen rapid detection in-house validation-a proof of concept.

Toxicol Sci. 2014 Jun;139(2):362-70. doi: 10.1093/toxsci/kfu046. Epub 2014 Mar 27. Johansson H., Rydnert F., Kuehnl J., Schepky A., Borrebaeck C.A.K., Lindstedt M. Abstract Chemical sensitization is an adverse immunologic response to chemical substances, inducing hypersensitivity in exposed individuals. Identifying chemical sensitizers is of great importance for chemical, pharmaceutical, and cosmetic industries, in order to prevent […]

Human blood dendritic cell subsets exhibit discriminative pattern recognition receptor profiles

Immunology. 2014 Jun;142(2):279-88. doi: 10.1111/imm.12252. Lundberg K., Rydnert F, Greiff L, Lindstedt M. Abstract Dendritic cells (DCs) operate as the link between innate and adaptive immunity. Their expression of pattern recognition receptors (PRRs), such as Toll-like receptors (TLRs) and C-type lectin receptors (CLRs), enables antigen recognition and mediates appropriate immune responses. Distinct subsets of human […]

Evaluation of high throughput gene expression platforms using a genomic biomarker signature for prediction of skin sensitization.

BMC Genomics. 2014 May 16;15:379. doi: 10.1186/1471-2164-15-379. Forreryd A., Johansson H., Albrekt A.S., Lindstedt M Abstract BACKGROUND: Allergic contact dermatitis (ACD) develops upon exposure to certain chemical compounds termed skin sensitizers. To reduce the occurrence of skin sensitizers, chemicals are regularly screened for their capacity to induce sensitization. The recently developed Genomic Allergen Rapid Detection […]

Prediction of skin sensitizers using alternative methods to animal experimentation.

Basic Clin Pharmacol Toxicol. 2014 Jul;115(1):110-7. doi: 10.1111/bcpt.12199. Epub 2014 Feb 18. Johansson H., Lindstedt M. Abstract Regulatory frameworks within the European Union demand that chemical substances are investigated for their ability to induce sensitization, an adverse health effect caused by the human immune system in response to chemical exposure. A recent ban on the […]

Skin sensitizers differentially regulate signaling pathways in MUTZ-3 cells in relation to their individual potency.

BMC Pharmacol Toxicol. 2014 Feb 11;15:5. doi: 10.1186/2050-6511-15-5. Albrekt A.S., Johansson H., Borrebaeck C.A.K., Lindstedt M. Abstract BACKGROUND: Due to the recent European legislations posing a ban of animal tests for safety assessment within the cosmetic industry, development of in vitro alternatives for assessment of skin sensitization is highly prioritized. To date, proposed in vitro […]

GARD – Genomic Allergen Rapid Detection. A Testing Strategy for Assessment of Chemical Sensitizers

Doctoral thesis defense date 2013-06-05 09:00     ISBN978-91-7473-519-2 Johansson, Henrik LU Abstract (Swedish) Popular Abstract in Swedish Vi lever i en tid och i ett samhälle där kemikalier har blivit en naturlig del av vår industrialiserade vardag. Till stor del ligger kemikalieindustrin bakom flera av de stora tekniska framsteg som gör att västvärlden har […]